Sugar acids and derivatives
Medchemexpress LLC Heparin calcium | 37270-89-6 | 3600-5000 Da | 50 MG
Heparin calcium (MW 3600-5000) is a low-molecular-weight heparin calcium salt used as an anticoagulant reagent for biochemical and pharmacological research. It forms a complex with antithrombin III to inhibit thrombin and other activated clotting factors, preventing fibrin formation. The material is a heterogeneous sulfated polysaccharide mixture provided as a dry reagent for laboratory use.
- Molecular weight 3600-5000 Da
- Anticoagulant activity via antithrombin III-mediated inhibition of clotting factors
- Intended for biochemical and pharmacological research applications
- Heterogeneous sulfated polysaccharide mixture, not a single defined molecule
- Supplied as a dry reagent suitable for in vitro assays
Medchemexpress LLC 4-Methylumbelliferyl-α-D-Glucopyranoside | 17833-43-1 | 99.99% | 338.31 | 25 MG
4-Methylumbelliferyl-α-D-Glucopyranoside is a fluorescent substrate for α-glucosidase, which releases the fluorescent moiety 4-methylumbelliferyl (4-MU) upon cleavage. 4-MU exhibits pH-dependent fluorescence excitation activity, with excitation wavelengths of 320 nm at low pH (1.97-6.72) and 360 nm at high pH (7.12-10.3). The emission wavelength of 4-Methylumbelliferyl-α-D-Glucopyranoside increases with decreasing pH, ranging from 445-455 nm. This compound can be utilized as a biomarker for Fabry and Pompe diseases to quantify α-glucosidase activity in infant blood spot samples.
- Fluorescent substrate for α-glucosidase.
- Releases fluorescent moiety 4-methylumbelliferyl (4-MU) upon cleavage.
- 4-MU has pH-dependent fluorescence excitation activity.
- Can be used as a biomarker for Fabry and Pompe diseases.
- Quantifies α-glucosidase activity in infant blood spot samples.
Medchemexpress LLC Integrin alpha 8 bet 50ug
Integrin -8/ -1 coordinates the recruitment of mesenchymal cells during renal organogenesis and recognizes RGD sequences in ligands such as TNC FN1 SPP1 TGFB1 TGFB3 and VTN It plays a role in multiple cellular interactions critical for organogenesis including NPNT as a functional ligand in nephrogenesis Integrin alpha 8 beta 1 Protein Human (HEK293 Flag His) is a recombinant protein dimer complex containing human-derived Integrin alpha 8 beta 1 protein expressed by HEK293 with C-10 His C-Flag labeled tag Integrin alpha 8 beta 1 Protein Human (HEK293 Flag His) has molecular weight of 85-140 kDa
![Research Products International Corp MUG [4-Methylumbelliferyl-B-D-glucuronide Trihydrate], 1 Gram](https://assets.fishersci.com/TFS-Assets/CCG/product-images/VN00006095-M65900-1.03.JPG-250.jpg)
Research Products International Corp MUG [4-Methylumbelliferyl-B-D-glucuronide Trihydrate], 1 Gram
Fluorescent substrate for β-D-Glucuronidase (GUS) encoded by the gusA gene isolated from E. coli. Fluorescence assay allows quantitation of GUS activity in protein extracts at peak excitation of 365 nm (UV) and a peak emission of 455 nm (blue).
Medchemexpress LLC Pentadecanoic acid-d29 | 130348-95-7 | MFCD00053332 | 271.58 | 10 MG
Pentadecanoic acid-d29 is the deuterium labeled Pentadecanoic acid. Pentadecylic acid is a saturated fatty acid with a 15-carbon backbone. It is for research use only.
- Used as a tracer
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
![Alkali Scientific 4 Methylumbelliferyl β D Galactopyranoside [4 Methylumbelliferyl β D Galactoside], 1 G](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000659794.jpg-250.jpg)
Alkali Scientific 4 Methylumbelliferyl β D Galactopyranoside [4 Methylumbelliferyl β D Galactoside], 1 G
Methylumbelliferyl Galactopyranoside (1g) is a high-purity biochemical reagent commonly used to assess the activity of enzymes involved in galactose metabolism, including galactosidases. This reagent is essential for enzyme-linked assays and other biochemical analyses in clinical and research laboratories. It is typically used in assays focused on carbohydrate metabolism, specifically in the breakdown of galactose and lactose derivatives. Methylumbelliferyl Galactopyranoside provides consistent, reproducible results, making it a valuable tool for studies involving glycosidase enzymes and other metabolic pathways that involve galactose-containing substrates.
Medchemexpress LLC D-(+)-Cellobiose | 528-50-7 | MFCD00136034 | 25 MG
D-(+)-Cellobiose is a water-soluble disaccharide and a crucial intermediate in the degradation of cellulose and hemicellulose. It serves as a carbon source for microorganisms in fermentation processes, which convert it into ethanol or other metabolic byproducts. This makes D-(+)-Cellobiose particularly valuable for applications in biofuel production, such as bioethanol.
- Water-soluble disaccharide
- Important intermediate in cellulose and hemicellulose degradation
- Utilized as a carbon source by microorganisms in fermentation
- Converts into ethanol and other metabolic products
- Significant application in biofuel production
- For research use only
Medchemexpress LLC Sodium zirconium cyclosilicate | 17141-74-1 | 95.0% | 10MG
Sodium zirconium cyclosilicate | 17141-74-1 | 95.0% | 10MG
Medchemexpress LLC AMG 333 | 1416799-28-4 | 99.8% | 453.32 | 25 MG
AMG 333 is an orally active and highly selective TRPM8 antagonist with an IC50 of 13 nM. It dose-dependently inhibits wet-dog shake behavior and blocks blood pressure elevation in rat models, making it a clinical candidate for the treatment of migraine.
- Orally active and highly selective TRPM8 antagonist
- Dose-dependently inhibits wet-dog shake behavior in the Icilin-induced wet-dog shake Sprague-Dawley rat model
- Dose-dependently blocks blood pressure elevation in the cold stimulation-induced blood pressure elevation Sprague-Dawley rat model
- A clinical candidate for the treatment of migraine
Medchemexpress LLC D-KLVFFA | 342877-55-8 | 99.3% | 723.90 | 10 MG
D-KLVFFA is an inhibitor of Amyloid-β assembly, with an IC50 of 2.6 μM. It can be utilized in Alzheimer's disease studies, offering insights into amyloid-beta aggregation pathways.
- Inhibits amyloid-β assembly
- Useful in Alzheimer's disease studies
- Molecular weight of 723.90
- Purity of 99.3%
Medchemexpress LLC Rose-β-D-gal | 138182-21-5 | MFCD00467206 | 99.7% | 329.73 g/mol | C14H16ClNO6 | 25 MG
Rose-β-D-Gal is a chromogenic β-galactosidase substrate that produces a pink/magenta color upon enzymatic cleavage. It is used to detect β-gal activity in biochemical and cell-based assays where a visible color change is required.
- Produces a pink/magenta chromogenic signal for β-gal activity detection.
- Suitable for enzymatic assays and staining applications.
- High reported purity (99.71%) for consistent performance.
- Solid reagent supplied in small milligram quantities for research use.
- Compatible with colorimetric readouts and microscopy.
Medchemexpress LLC Protac α-synuclein degrader 5 | 2781922-42-5 | 100.0% | 767.78 g/mol | C39H41N7O10 | 10 MG
PROTAC α-synuclein degrader 5 is a small-molecule PROTAC designed to selectively target and promote degradation of α-synuclein aggregates in cellular models. Supplied as a high-purity solid for preclinical research, it shows dose-dependent activity in fibril-seeding assays and is formulated for in vitro and in vivo use.
- Selective degradation of α-synuclein aggregates (DC50 ≈ 7.5 μM, Dmax 89%).
- Demonstrated reduction of aggregates within 48 hours in PFF seeding cell models.
- High-purity solid suitable for biochemical and cellular assays.
- High solubility in DMSO for in vitro applications (≥100 mg/mL).
- Compatible with in vivo formulation protocols and frozen storage for stability.