Sugar acids and derivatives
BIOHIPPO T-bet-TAL-BSD LV
T-bet-TAL-BSD is a transcription factor reporter lentiviral vector designed to monitor the target signaling pathway in living cells The construct carries a fluorescent reporter gene under the control of pathway responsive elements and includes a blasticidin selection marker to generate stable cell pools The lentivirus is provided as a ready to use VSV G pseudotyped preparation for efficient gene delivery and stable genomic integration Each vial provides a nominal titer of 5x10E6 transducing units TU Typical applications include pathway activation studies assay development compound screening and mechanism of action research The system is suitable for human and mouse cells and can be read using standard fluorescence microscopy flow cytometry or luciferase assays depending on the reporter gene This product is intended for research use only and is not for diagnostic or therapeutic procedures
Apexbio Technology LLC β-Pompilidotoxin 216064-36-7 25mg
-Pompilidotoxin ( -PMTX CAS 216064-36-7) is a peptide neurotoxin isolated from the venom of the solitary wasp Batozonellus maculifrons Composed of 13 amino acids (C71H124N22O17) -PMTX modulates neuronal excitability by selectively slowing the inactivation of voltage-gated sodium (Na ) channels without affecting cardiac Na channels This action is thought to involve interaction with neurotoxin receptor site 3 on the extracellular surface of neuronal Na channels Compared to -pompilidotoxin -PMTX exhibits greater potency in enhancing synaptic transmission at neuromuscular junctions -PMTX serves as a valuable tool for investigating Na channel kinetics and the molecular mechanisms regulating synaptic transmission
Apexbio Technology LLC HyperTrap Heparin FF Column 1ml
HyperTrap Heparin FF Column is an affinity chromatography medium designed for the purification of heparin-binding biomolecules The column exploits the strong ionic and specific interactions between immobilized heparin and target proteins such as growth factors coagulation factors and certain enzymes enabling selective retention and efficient separation from complex biological mixtures This tool is widely utilized in the isolation and characterization of heparin-binding proteins investigation of protein glycosaminoglycan interactions and purification of bioactive factors for downstream functional assays and structural analyses
BIOHIPPO T-bet-TAG-BSD LV
T-bet-TAG-BSD is a transcription factor reporter lentiviral vector designed to monitor the target signaling pathway in living cells The construct carries a fluorescent reporter gene under the control of pathway responsive elements and includes a blasticidin selection marker to generate stable cell pools The lentivirus is provided as a ready to use VSV G pseudotyped preparation for efficient gene delivery and stable genomic integration Each vial provides a nominal titer of 5x10E6 transducing units TU Typical applications include pathway activation studies assay development compound screening and mechanism of action research The system is suitable for human and mouse cells and can be read using standard fluorescence microscopy flow cytometry or luciferase assays depending on the reporter gene This product is intended for research use only and is not for diagnostic or therapeutic procedures
Medchemexpress LLC Beta-D-glucopyranosyl nitromethane | 81846-60-8 | 99.5% | C7H13NO7 | 25 MG
Beta-D-Glucopyranosyl nitromethane is a glycosyl derivative of nitromethane, presented as a salt of a strongly basic anion exchanger in the OH cycle. This chemical is intended for research use only, serving as a laboratory chemical and for the manufacture of substances.
- Glycosyl derivative of nitromethane.
- Presented as a salt of a strongly basic anion exchanger in the OH cycle.
- Suitable for laboratory chemical applications.
- Used in the manufacture of substances.
Medchemexpress LLC Zen-3694 | 1643947-30-1 | 99.7% | 333.39 | C19H19N5O | 25MG
BET-IN-19 is a potent small-molecule BET bromodomain inhibitor for research use. It inhibits hIL-6 mRNA transcription and c-myc activity in AML MV4-11 cells (IC50 ≤ 0.3 μM). The compound has molecular formula C19H19N5O, molecular weight 333.39, and reported purity ≈99.7%; it is supplied as a powder and is typically stored at -20°C (powder) or at -80°C in solvent for longer term.
![Apexbio Technology LLC heparin cofactor II precursor fragment [Homo sapiens] 25mg](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000097080.png-250.jpg)
Apexbio Technology LLC heparin cofactor II precursor fragment [Homo sapiens] 25mg
Heparin cofactor II precursor fragment is a thrombin inhibitor peptide targeting human thrombin (factor IIa) It is designed to inhibit thrombin activity thereby modulating blood coagulation pathways Heparin cofactor II precursor fragment exerts its biological activity primarily through serine protease inhibition facilitated in the presence of heparin or dermatan sulfate Based on these pharmacological properties heparin cofactor II precursor fragment holds research potential in investigating thrombin inhibition mechanisms blood coagulation pathways and conditions associated with altered coagulation such as heparin cofactor II deficiency and hypercoagulability disorders
Medchemexpress LLC 4-methylumbelliferyl β-D-cellobioside | 72626-61-0 | MFCD00063279 | >98.0% | C22H28O13 | 10MG
4-Methylumbelliferyl β-D-cellobioside is a fluorogenic glycoside substrate used to measure cellulase and related β-glucosidase activity. Enzymatic hydrolysis liberates 4-methylumbelliferone, a fluorescent reporter commonly quantified in biochemical and enzymatic assays for activity and kinetics studies.
- Fluorogenic substrate for cellulase and β-glucosidase assays.
- Releases fluorescent 4-methylumbelliferone upon enzymatic cleavage.
- High purity (>98.0%) suitable for quantitative assays.
- Known molecular weight (500.45 g·mol⁻¹) and chemical formula (C22H28O13).
- Available in small research-scale quantities for laboratory use.
Medchemexpress LLC Acyl-CoA oxidase | 61116-22-1 | 100 U
Acyl-CoA oxidase (ACO) is a peroxisomal catalyst and a key rate-limiting enzyme in the process of peroxisomal fatty acid β-oxidation. It participates in lipid catabolism and phytohormone biosynthesis pathways.
- Peroxisomal catalyst
- Key rate-limiting enzyme in peroxisomal fatty acid β-oxidation
- Participates in lipid catabolism and phytohormone biosynthesis pathways
- Appearance: solid, light yellow to yellow
Medchemexpress LLC Ethyl glucuronide | 17685-04-0 | 99.2% | 222.19 | 10 MG
Ethyl glucuronide is an endogenous metabolite and a metabolite of ethanol. It serves as a biomarker for ethanol exposure, accumulating in hair and reflecting alcohol intake over time. Ethyl glucuronide is also an agonist for TLR4.
- Endogenous metabolite
- Metabolite of ethanol
- Biomarker for ethanol exposure
- Accumulates in hair
- Reflects alcohol intake over time
- Agonist for TLR4
Medchemexpress LLC Integrin alpha V beta 8 protein, mouse | ≥95.0% | 20UG
Integrin alpha V beta 8 protein (mouse) is a recombinant heterodimer expressed in HEK293 cells with a C-terminal His tag, intended for research use in studies of integrin signaling, ligand binding, and cell adhesion. The product is supplied as a purified protein in defined sizes and is characterized by a reported purity and molecular weight range suitable for biochemical and cell-based assays.
- Recombinant mouse integrin heterodimer suitable for functional assays.
- Produced in HEK293 expression system to preserve mammalian modifications.
- His tag facilitates purification and detection in biochemical workflows.
- High purity supports reliable assay results (≥95.0%).
- Supplied in defined sizes for flexible experimental needs.
- Molecular weight consistent with alpha and beta subunits (80-140 kDa).
Medchemexpress LLC IL-1RA/IL-1F3 Porci 50ug | 50ug
IL-1RA/IL-1F3 proteins are powerful anti-inflammatory antagonists in the interleukin 1 family specifically targeting the pro-inflammatory cytokines IL1B and IL1A This protein counteracts the inflammatory effects of IL1 playing a critical role in preventing immune dysregulation and preventing uncontrolled systemic inflammation triggered by a variety of innate irritants including pathogens IL-1RA/IL-1F3 Protein Porcine is the recombinant Porcine-derived IL-1RA/IL-1F3 protein expressed by E coli with tag free
Medchemexpress LLC Integrin alpha V bet 5ug
Integrin V beta 3 proteins specifically the -V (ITGAV) subunit are multifunctional receptors for ligands such as vitronectin and fibronectin and recognize RGD sequences ITGAV ITGB3 binds fractalkine and acts as a coreceptor in CX3CR1-dependent signaling Integrin alpha V beta 3 Protein Human (HEK293 C-His) is a recombinant protein dimer complex containing human-derived Integrin alpha V beta 3 protein expressed by HEK293 with C-10 His labeled tag Integrin alpha V beta 3 Protein Human (HEK293 C-His) has molecular weight of 90 31 110-150 kDa respectively
Medchemexpress LLC 2H-1-benzopyran-2-one, 7-(beta-D-glucopyranosyloxy)-4-methyl- | 18997-57-4 | MFCD00063694 | 99.9% | 338.31 g/mol | C16H18O8 | 10MM 1ML
4-Methylumbelliferyl β-D-glucopyranoside is a coumarin-based fluorogenic substrate used to measure β-glucosidase and related enzyme activities. Enzymatic hydrolysis releases the fluorescent 4-methylumbelliferone (4-MU), which emits near 445-454 nm; excitation is pH-dependent. The product is supplied as a 10 mM solution in DMSO (1 mL) and is suitable for fluorescence-based biochemical assays.
![Medchemexpress LLC 4-methyl-5-[2-(4-morpholin-4-ylanilino)pyrimidin-4-yl]-1,3-thiazol-2-amine | 693228-63-6 | MFCD14155805 | 99.1% | 368.46 g·mol⁻¹ | C18H20N6OS | 25 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000241055.png-250.jpg)
Medchemexpress LLC 4-methyl-5-[2-(4-morpholin-4-ylanilino)pyrimidin-4-yl]-1,3-thiazol-2-amine | 693228-63-6 | MFCD14155805 | 99.1% | 368.46 g·mol⁻¹ | C18H20N6OS | 25 MG
CYC-116 is a small-molecule inhibitor of Aurora A and Aurora B kinases with low-nanomolar inhibitory potency. It is used as a research reagent to investigate mitotic signaling and cell-cycle regulation and is supplied as a purified solid for in vitro studies.
- Potent dual Aurora A and B inhibitor with Ki ≈8-9 nM.
- Suitable for studying mitotic signaling and cell-cycle regulation in vitro.
- High purity (>99.0%) for reliable experimental results.
- Chemical formula C18H20N6OS; molecular weight 368.46 g·mol⁻¹.
- Available in multiple small-quantity pack sizes for laboratory use.